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Metabolic syndrome may increase the risk of mortality in women suffering from breast cancer – research

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New Delhi. A study has revealed that metabolic syndrome, which increases the risk of heart disease, type 2 diabetes and stroke, may increase the risk of mortality in women suffering from breast cancer. Metabolic syndrome is defined as obesity with high blood pressure, high blood sugar, abnormal cholesterol.

The findings, published online by Wiley in the American Cancer Society review journal Cancer, indicate that metabolic syndrome and obesity have different associations with breast cancer subtype and mortality risk.

The analysis was based on 63,330 postmenopausal women without prior breast cancer as well as those with normal admission mammograms and metabolic scores (0-4). After a mean follow-up of 23.2 years, there were 4,562 breast cancer events and 659 deaths from breast cancer (breast cancer mortality).

Researchers found that regardless of obesity, high metabolic score (3-4) increased the risk of poor prognosis estrogen receptor (ER) positive, progesterone receptor (PR) negative breast cancer and 44 percent of breast cancer mortality. There is more risk.

On the other hand, obesity predicted ER-positive and PR-positive cancers well, regardless of metabolic score.

Only women with severe obesity had a higher risk of death from breast cancer. Postmenopausal women with higher metabolic scores have a higher risk of breast cancer death, said lead author Rowan T. Klebowski, of The Lundquist Institute in California.

Rowan said the metabolic score can be easily determined and treated by checking waist circumference and blood pressure measurements along with a history of cholesterol, diabetes and high blood pressure during a routine visit to any health facility. .

–IANS

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